Saturday, June 30, 2012

Darvish says he's 'not worthy' of being All-Star

Associated Press Sports

updated 8:09 p.m. ET June 29, 2012

ARLINGTON, Texas (AP) - Yu Darvish doesn't think he's deserving of being an All-Star in his first season in the major leagues, despite his 10-4 record with the Texas Rangers.

"Personally, do I feel like I'm an All-Star? I don't think so," Darvish said through his translator Friday. "And I'm also hearing there's a possibility that I might start an All-Star game, and to me that's totally out of context. ... Am I going to be an All-Star? I don't know. But do I think that I'm worthy? Probably not."

The Japanese standout made his comments two days before the All-Star teams will be announced. He also makes his next start for the Rangers on Sunday, in the finale of a four-game series against Oakland.

Darvish was a five-time All-Star and two-time Pacific League MVP over the past seven seasons in Japan. The Rangers paid more than $107 million to sign the 25-year-old pitcher last winter.

"I think that the fact that I'm Japanese, the first year over here, the Texas Rangers paid a lot of money for me to come over here, I think the fact that I am an All-Star candidate, I think that's more of a buildup by just who I am and where I came from," he said.

The AL All-Star manager is the Rangers' Ron Washington.

Darvish was tied for the AL lead with 10 wins and had a 3.57 ERA after beating Detroit on Tuesday night, when he became only the second major leaguer in a half-century to win his first seven career home starts.

The 6-foot-5 right-hander has 106 strikeouts and 50 walks in 95 2-3 innings over 15 starts. He was fourth in the AL in strikeouts, but also had the third-most walks in the league. He had the most walks until his last start when he had his fourth 10-strikeout game while walking only one batter.

"Whether I'm not leading anymore, still I'm giving up more walks than I should," he said. "That's something that I'm going to improve on in the future."

? 2012 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.


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HBT Extra: Are we in a pitchers' era now?

HBT Extra: Craig Calcaterra and Tiffany Simons discuss Aroldis Chapman's somersault celebration, whether this is officially the pitchers' era, Zack Greinke's future, and more.

Source: http://nbcsports.msnbc.com/id/48021543/ns/sports-baseball/

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Commercial Automobile Insurance security Defends Businesses ...

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After 13 days in orbit, China's first female astronaut returns to Earth (+video)

The three-member crew, which includes China's first female astronaut, emerged grinning from their Shenzhou?9 space capsule.

By Christopher Bodeen,?Associated Press / June 29, 2012

Chinese astronauts Jing Haipeng, Liu Wang and Liu Yang, China's first female astronaut, salute in front of the re-entry capsule of China's Shenzhou 9 spacecraft in Siziwang Banner, Inner Mongolia Autonomous Region.

XINHUA

Enlarge

China's first female astronaut and two other crew members emerged smiling from a capsule that returned safely to Earth on Friday from a 13-day mission to an orbiting module that is a prototype for a future space station.

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' + google_ads[0].line2 + '
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'; } else if (google_ads.length > 1) { ad_unit += ''; } } document.getElementById("ad_unit").innerHTML += ad_unit; google_adnum += google_ads.length; return; } var google_adnum = 0; google_ad_client = "pub-6743622525202572"; google_ad_output = 'js'; google_max_num_ads = '1'; google_feedback = "on"; google_ad_type = "text"; google_adtest = "off"; google_image_size = '230x105'; google_skip = '0'; // --> A capsule carrying three Chinese astronauts ? one that nation's first women in that role ? touched down. Chip Reid reports.

The?Shenzhou?9?parachuted to a landing on the grasslands of the country's sprawling Inner Mongolia region at about 10 a.m. (0200 GMT). China declared the first manned mission to the Tiangong 1 module ? the space program's longest and most challenging yet ? a major stride ahead for the country's ambitious space program.

About an hour later, mission commander and veteran astronaut Jing Haipeng, 45, emerged from the capsule, followed by crew mates Liu Wang, 43, and 33-year-old Liu Yang, China's first female astronaut.

The three, all experienced air force pilots, were lifted on to folding chairs and appeared in good health. They smiled, waved, chatted and saluted as state television ran live footage from the landing site.

"Tiangong 1, our home in space, was comfortable and pleasant. We're very proud of our nation," Liu Yang told national broadcaster CCTV.

Space program commander, Gen. Chang Wanchuan, declared the astronauts in good health and declared the mission "completely successful."

He was followed by Premier Wen Jiabao, who said the mission marked "absolutely important progress" for the space program.

The mission had included both remote control and piloted dockings with the module and extensive medical monitoring of the astronauts as part of preparations for manning a permanent space station.

China's next goals include another manned mission to the module originally scheduled for later this year but which may be delayed depending on an evaluation of the?Shenzhou?9?mission and the condition of the Tiangong 1. China has been extremely cautious and methodical in its manned missions, with more than three years passing since the previous one, and all four have been relatively problem-free.

Chen Shanguang, director for the Chinese Astronaut Research and Training Center, told a news conference that preparations and selection of astronauts were already under way for the?Shenzhou?10 mission.

Tiangong 1 is due to be retired in a few years and replaced with a permanent space station around 2020 that will weigh about 60 tons, slightly smaller than NASA's Skylab of the 1970s and about one-sixth the size of the 16-nation International Space Station that China was barred from participating in, largely on objections from the United States. Possible future missions could include sending a rover to the moon, possibly followed by a manned lunar mission. Launched June 16 from the Jiuquan center on the edge of the Gobi desert in northern China,?Shenzhou?9?is the latest success for China's manned space program that launched its first astronaut, Yang Liwei, into space in 2003, making China just the third nation after Russia and the U.S. to achieve that feat. China would also be the third country after the United States and Russia to send independently maintained space stations into orbit.

Earlier in the week, a spokeswoman said China spent 20 billion yuan ($3.1 billion) on its space program between 1992 and 2005 ? a rare admission for a program with close links to the secretive military. By the time the next?Shenzhou?mission is completed, Beijing will have spent an additional 19 billion yuan ($3 billion), the spokeswoman said.

Wang Zhaoyao, director of China's manned space program office, said the program mirrors the rising global status of China.

"For any country, for any people, a space program is indispensable," Wang said.

___

Associated Press writer Didi Tang contributed to this report.

Source: http://rss.csmonitor.com/~r/feeds/csm/~3/aPs6zC3NMNM/After-13-days-in-orbit-China-s-first-female-astronaut-returns-to-Earth-video

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Friday, June 29, 2012

Meribel Olympic Sports Centre The Skiing Blog

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Graham Nash Works | Arts & Entertainment | Atlantic City Weekly

Neil Young by Graham Nash

Photo by Copyright Graham Nash 2012

Graham Nash has been playing with Crosby, Stills and Nash since 1968. Although he and his at-the-time new band mates ? Crosby, a former member of the Byrds; Stills of Buffalo Springfield, and Nash of the Hollies ? would become one of the biggest radio and concert sensations of the late 1960s and 1970s through today, the trio ? which would also work with Neil Young for many projects ? wasn?t quite ready for its first concert:?

The Atlantic City Pop Festival, held at the Atlantic City Race Course in Mays Landing, just before Woodstock in August 1969.?

?We didn?t play it,? says Nash, on a tour stop with CSN in Providence, Rhode Island. (The band is on the road through October and returns to the Borgata in Atlantic City on Saturday, June 30.)?

Although CSN was to debut live at the A.C. Pop Fest, with its name listed on the festival?s official posters and T-shirts, etc., Nash doesn?t quite remember the circumstances. ?

?I?m not sure to be honest,? he says. ?I?ve been asked this question twice within the last month. ? I believe that we needed more practice. Don?t forget Woodstock was only the second gig we ever played together live. ?

?I think we might have needed more rehearsal or something. Something was going on and we didn?t play that Atlantic City [date, but] there were people who swore they saw us there!??

Aside from singing and playing on such classic tunes as ?Almost Cut My Hair,? ?Teach Your Children,? ?Our House? and ?Chicago,? Nash has been interested in art and photography for decades. ?

Although he has had exhibits of his photography in the past, his paintings ? mainly acrylics ? are being unveiled for the first time beginning this Thursday (June 28) in Stone Harbor.?

While CSN plays the Borgata, Nash?s exhibit ?The Art of Graham Nash? will be on display at Ocean Galleries (9618 Third Ave., Stone Harbor) through Sept. 30. ?

However, on July 1, Nash will be at the gallery in person for a reception between 7-10pm where he will sign purchased art.?

?This exhibit has never been seen before,? says Nash. ?These paintings. I?ve been working on this [exhibit] for about a year and a half now.?

?This whole experience is fresh. It was amazing to me that when the gallery owners came out to my house in Los Angeles and saw my work it was their response that got me excited because, I mean, they?re supposed to know what they?re doing ? they?ve had an art gallery for a couple decades now and they?re this excited! It was shocking to me.? ?

So Nash decided to share his intriguing imagery with the world.?

?Why not let other people see them?? Nash says. ?You know? It?s brand new to me and it?s going to be exciting.??

Exciting for southern New Jersey folks as well, as the Ocean Galleries exhibit is the world premiere of Nash?s paintings of images and people such as Neil Young. ?

Nash says he is already working on another exhibit of different works.?

?I?ve done another exhibit of very serious work that I?ve been doing,? says Nash. ?

?Almost brutal images of things that disturb me. ... It?s hard to say what they are. They are a combination of painting and photographs and images that I made collages of ? interesting work. And there will only be seven pieces in the entire exhibit. Six of them will be four-feet-square and one image will be four-feet-high by 12-feet long.??

Aside from the images that will be on display at Ocean Galleries this summer, Nash?s Web site shows more than 40 photographs the 70-year-old multi-faceted artist has taken over the years.?

?I?ve been a photographer longer than I?ve been a musician,? says Nash. ?The first portrait that I ever took where I thought I had something was of my mother when I was 11.??

On the Web site, there is a photo of Bob Dylan playing live at Madison Garden for the George Harrison-organized Concert for Bangladesh. ?

?Oh, yes I was there. That?s Leon Russell there behind him. I was there to purely watch George pull off a piece of wonderfulness. It was a great, great concert.??

So, has Nash shown any of his subjects his paintings of them??

?No, neither David [Crosby] or Stephen [Stills] Neil [Young] or Joni [Mitchell] have seen any of these. It?s kind of wild; it would be interesting to hear their reaction.? The Neil Young image was painted from a photograph Nash took of the musician ?years ago.??

RELATED: INTERVIEW WITH STEPHEN STILLS ('IT'S DEJA VU ALL OVER AGAIN')

?I really like it and I blew it up larger on canvas and painted it. There are several in there because not only are they all different colors and different interpretations, but I wrote a line from a Neil song into every painting.??

One of the Neil Young images is called ?Neil Young ? Hurricane,? which is a line from his song, ?Like a Hurricane.? There is also Neil Young ? Old Man, with, along his shoulder line, I?ve written a line from his song ?Old Man.? Just pushing it all forward.?

Like fellow musician Ronnie Wood of the Rolling Stones, who also has a southern New Jersey art exhibit (at the Golden Nugget Atlantic City through July, see images here), Nash prefers acrylic paint to oils. ?

?Right now, I?m loving acrylic,? says Nash. ?I don?t do [work] in oil. I?m too impatient. It takes too long to dry. It takes days to dry. It drives me crazy.??

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'; commentSection.appendChild(commentDiv); } } } function validateCommentForm(form){ var fieldEmail = document.getElementById("field.email"); var fieldName = document.getElementById("field.name"); var nameValue = fieldName.value; var emailValue = fieldEmail.value; var filter = /^([a-zA-Z0-9_\.\-])+\@(([a-zA-Z0-9\-])+\.)+([a-zA-Z0-9]{2,4})+$/; if (filter.test(emailValue)) { var fieldBody = document.getElementById("field.body") var bodyValue = fieldBody.value; bodyValue = bodyValue.replace(/&/g,"&"); bodyValue = bodyValue.replace(/,"/g,">"); bodyValue = bodyValue.replace(/\r\n/g,"

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Thursday, June 28, 2012

7.2 Trillion Degrees Fahrenheit! (talking-points-memo)

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Rare 'Green Rust' Offers Glimpse of Ancient Seas

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Anti-Taliban leader shot dead in Pakistan

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Wednesday, June 27, 2012

five Prime Factors Infant Boomers Have to Do Just before Beginning ...

You are here: Home / Business / five Prime Factors Infant Boomers Have to Do Just before Beginning a Home Based Small business




five Top rated Factors Baby Boomers Must Do Before Starting a House Small business

Don?t quit your day job just however.For anyone who is an infant boomer wanting to get started a house organization, you will discover five essentials things you will need to do 1st.

Leaving the security of a job with an established 401(k) program, health insurance coverage or other positive aspects can make a genuine tug of war for baby boomers who need to pursue their dreams of owning their own enterprise.

Analyze Your Exit Technique

At the time of this writing, the youngest of the baby boomers are turning 42 along with the oldest are turning 60. No matter where you fall into this group, analyzing and preparing your exit technique from your job will likely be vital to your long-term good results as a home business enterprise entrepreneur. Do you might have adequate savings If you?re married, will you be capable of participate in your spouse?s well being insurance coverage

Make a Financial Strategy

How much is your salary now What are your fixed, variable and frivilous expenditures Producing a solid program in order that you and your family will know precisely what the financial picture might be until your business gets off the ground and starts creating income.

Choosing an Enterprise Model and Legal Entity

There are actually various small business models to select from; house party plans, consulting, and affiliate marketing and advertising to name a handful of. You will need to make the selection according to your personality and what that you are best-suited for. Picking out a legal entity for the business enterprise should really be discussed with a tax accountant or your lawyer. Possibilities are sole proprietor, LLC or Subchapter S- Corp.

Set Small business Benchmarks

You would not travel across the country with no a road map, your company will be the exact same. Setting monetary and business-building benchmarks will help you to create a focused strategy that may allow you to to reach your good results.

Get a Physical

What does finding a physical have to do together with your company The moment you leave your job, probably your well being insurance will modify and as unfair because it may perhaps be, looking to get new well being insurance coverage when in your 40?s, 50?s or 60?s may be tricky. When pursuing your dreams of a house small business is something you happen to be most likely quite passionate about, if you don?t have fantastic well being to enjoy the rewards of the efforts, then not much else is vital.

The baby boomer generation is like no other before it or after it. Technically, we are regarded as middle-aged, but we?re anything but middle-aged in mind, body and spirit. We know there is certainly far more meaning to life than a commute to an unrewarding 9-5 job, but you will find also significant actions we should take 1st. Planning and preparing for the household small business now will result in much less headache?s later on.

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France's Hollande tells Suu Kyi will back Myanmar transition

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Microsoft to buy Yammer for $1.2 billion

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NASA's Seven Minutes of Terror: Curiosity's precarious Mars landing explained (video)

NASA's Seven Minutes of Terror Curiosity's precarious Mars landing explained video

Edited and scored with the dramatic tension of a summer blockbuster trailer, NASA's put together a gripping short clip that dresses down Curiosity's mission to Mars for the layman. The "car-sized" rover, set to touchdown on August 5th of this year at 10:31PM PDT, is currently journeying towards the Red Planet on a suicide mission of sorts, with the success of its make it or break it EDL (enter, descent, landing) wracking the nerves of our Space Agency's greatest minds in advance. Their cause for concern? A period of radio silence, dubbed the "seven minutes of terror" for the amount of time it takes a signal to reach Earth, during which the craft will have already either smashed disastrously into the Martian landscape or nestled perfectly down from the ascend phase on a 21ft long tether. The logistics involved are so numerous and prone to error -- slowing the craft from 13,000 mph to 0 mph and then deploying, detaching and avoiding collision with the supersonic parachute for starters -- that it's a wonder the government ever signed off on the project. If it all does come off without a hitch, however, the ladies and gents down at Pasadena's Jet Propulsion Laboratory certainly deserve several thousand bottles of the finest bubbly taxpayers' money can buy. Click on past the break to gape at the sequence of engineering feats required to make this landing on terra incognita.

Continue reading NASA's Seven Minutes of Terror: Curiosity's precarious Mars landing explained (video)

NASA's Seven Minutes of Terror: Curiosity's precarious Mars landing explained (video) originally appeared on Engadget on Mon, 25 Jun 2012 21:29:00 EDT. Please see our terms for use of feeds.

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For cleaner laundry, add diamonds

5 hrs.

Laundry detergent laced with teeny, tiny diamonds removes fats and dirt at lower temperatures than the blingless variety, according to new research.

The nanodiamonds -- pieces of carbon less than ten thousandths the diameter of a human hair ? were added powder detergent to see if they could scrub out grime that typically requires hot water cycles to remove.

?We found that the 5 nanometer diamonds changed the way detergents behaved at 25 degrees centigrade (77 degrees Fahrenheit), doubling the amount of fat removed,? Andrew Marsh, a chemist at the University of Warwick in England, said in a news release.?

?Even at temperatures as low as 15 degrees centigrade (59 degrees F), otherwise hard-to-remove fat could be solubilized from a test surface.?

Without the diamonds, water temperatures between 60 and 90 C (140 and 194 F) are required to get such stains out of laundry.?

The lower temperature water afforded by the bling, the team notes, should help people save on their energy bills. Of course, they may have to spend that savings on the pricier detergent.

The research appears in the journal Applied Materials and Interfaces.?

John Roach is a contributing writer for msnbc.com. To learn more about him, check out his website and follow him on Twitter. For more of our Future of Technology series, watch the featured video below.

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Tuesday, June 26, 2012

Forgotten star cluster now found useful in studies of Sun and hunt for Earth-like planets

Forgotten star cluster now found useful in studies of Sun and hunt for Earth-like planets

Monday, June 25, 2012

A loose group of stars that was known for over 180 years but never before studied in detail has been revealed to be an important new tool in the quest to understand the evolution of stars like the Sun, and in the search for planets like Earth. "We have discovered that a previously unappreciated open star cluster, which is a little younger than our Sun, holds great promise for use as a standard gauge in fundamental stellar astrophysics," said Jason T. Wright, an assistant professor of astronomy and astrophysics at Penn State University, who conceived and initiated the research.

Wright's research team's first paper on the cluster, known as Ruprecht 147 or NGC 6774, has been submitted to the Astronomical Journal for publication. Team member Jason Curtis, a graduate student in Wright's lab, led the work for this paper and will present the team's project in Barcelona, Spain, later this month at the 17th Cambridge Workshop on Cool Stars, Stellar Systems, and the Sun.

When searching for planets with an Earth-like mass and an orbit that allows liquid water to exist on the surface, astronomers often search around stars the mass of the Sun and smaller. "The Ruprecht 147 cluster is very unusual and very important astrophysically because it is close to Earth and its stars are closer to the Sun's age than those in all the other nearby clusters," Wright said. "For the first time, we now have a useful laboratory in which to search for and study bright stars that are of similar mass and also of similar age as the Sun. When we discover planets around Sun-like and lower-mass stars, we will be able to interpret how old those stars are by comparing them to the stars in this cluster."

Wright's team has shown that Ruprecht 147 is 800 to 1,000 light years from Earth, which is so close that it is bright enough to be seen with binoculars in late-summertime skies in the constellation Sagittarius. "All of the other nearby clusters astronomers study contain stars much younger than the Sun, and all of the older stars are more than 3,000 light years away. So this cluster, being both old and close, provides a unique opportunity," Wright said. Although it appears to be relatively large on the sky, the cluster can be difficult to spot because it is not very compact and it is located in the densest, brightest region between Earth and the center of the Milky Way galaxy.

To study the Ruprecht 147 cluster, which is much larger on the sky than most objects astronomers study, the Wright's team had to use some specialized, wide-field cameras -- including those on the MMT telescope in Arizona and the Canada-France-Hawaii Telescope on Mauna Kea in Hawaii -- in order to get its many stars within the frame of view. "Even with these wide-field cameras, we've had to build mosaics of images to cover the whole cluster and to take very quick snapshots so that we don't overexpose the brightest stars, Wright said. "Most modern telescopes weren't designed for clusters so bright and close."

When the object was first discovered in 1830 by British astronomer John Herschel, he described it as "a very large straggling space full of loose stars." He subsequently included it in the General Catalog of astronomical objects, which he compiled based on the observations of his father William Herschel. "The cluster was rediscovered in the 1960s by Jaroslav Ruprecht, which is how it got its current name, but until now no astronomers paid it any special attention, probably because many presumed it was an asterism -- a chance alignment of unrelated stars," Wright said.

Wright's team's work has proven, for the first time, that the Ruprecht 147 cluster is only a bit younger than the Sun on the astronomical time scale. The stars in Ruprecht 147 are about 2.5-billion years old, or about half the age of the Sun, and about the age the Sun was when the first multicellular life emerged on Earth.

The team's initial observations also have measured the distance to Ruprecht 147, as well as the directions and velocities of its stars to verify that they are moving together through space in three dimensions, both across the sky and in the same angle away from Earth. These observations confirm that these stars are members of a true cluster, not just a random pattern on the sky. Wright's team already has identified 100 stars as members of the cluster, and is working to find more.

Wright said that most of the work for this initial paper was done by Jason Curtis as part of his dissertation research. Curtis's work includes observations with the Canada France Hawaii Telescope (CFHT) and the Keck telescope in Hawaii, the Lick Observatory in California, and the MMT Observatory in Arizona.

"This project is exciting for me as a graduate student because it gives me the opportunity to use the latest astronomy techniques and instrumentation to explore a star cluster that has never before been investigated to this extent," Curtis said. "While this project has given me training in well-established, fundamental methods of astronomy observation and analysis, it is also opening up new doors to cutting-edge astrophysics research." For further studies, Curtis is participating in observations with the Magellan telescope in Chile and NASA's orbiting Chandra X-Ray Telescope.

In addition to Wright and Curtis, other co-authors of the team's first scientific paper include Angie Wolfgang, of the University of California, Santa Cruz; John Brewer, of Yale University; and John Asher Johnson of the California Institute of Technology. The US National Science Foundation provided financial support for this research.

"Our project with this important cluster is just beginning," Wright said "Eventually, it is going to let us find and study nearby stars with a mass like the Sun's, to help in the hunt for Earth-like planets, and to test and improve the models astronomers use to understand the evolution of stars including our own Sun."

###

Penn State: http://live.psu.edu

Thanks to Penn State for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

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Monday, June 25, 2012

Mobile Miscellany: week of June 18th, 2012

Mobile Miscellany week of June 18th, 2012

Not all mobile news is destined for the front page, but if you're like us and really want to know what's going on, then you've come to the right place. This past week, we learned of the first market outside of China for ZTE's new Grand X smartphone, and received news that both the Sony Xperia U and Xperia P will arrive in Australia. These stories and more await after the break. So buy the ticket and take the ride as we explore the "best of the rest" for this week of June 18th, 2012.

Continue reading Mobile Miscellany: week of June 18th, 2012

Mobile Miscellany: week of June 18th, 2012 originally appeared on Engadget on Sat, 23 Jun 2012 21:15:00 EDT. Please see our terms for use of feeds.

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Promising Pancreatic Cancer Treatment


(Ivanhoe Newswire) ? There are more than 42 thousand new diagnosed cases of pancreatic cancer in the U.S., and of those, more than 35 thousand have resulted in death. Now researchers are looking at a new treatment that could change how we view pancreatic cancer.

A novel chemotherapeutic agent, the highly selective MEK1/2 inhibitor BAY 86-9766, may be a promising future treatment for pancreatic ductal adenocarcinoma (PDAC). In a preclinical therapeutic study, BAY 86-9766 was evaluated in one of the most aggressive mouse models for PDAC. The researchers induced endogenous genetic alterations in these mice, and within eight weeks, the mice developed invasive, lethal PDAC. These genetic alterations closely mimic what is found in most human cases of the disease.

Nicole Teichmann, Ph.D., of the Klinikum rechts der Isar at the Technische Universit?t M?nchen in Munich, Germany was quoted as saying, "We showed in our endogenous mouse model that our novel chemotherapeutic agent leads to dramatic tumor shrinkage after only one week of treatment. Moreover, the therapy was as effective in animals with advanced tumors and ascites, which is often the case if patients come to the clinic."

A daily treatment of 25 mg/kg with BAY 86-9766 prolonged the survival of the mice in the study compared to their 'placebo'-treated counterparts; median survival advantage was 20 days. The treatment caused dramatic tumor regression after only one week and was effective in animals with advanced tumors and ascites, which is often how patients present to the clinic. "We were really surprised that the tumor load dramatically decreases after one week of therapy and also that the treatment conferred such a strong overall survival benefit. In our hands, this is the first targeted drug to have shown such strong tumor effects in an endogenous mouse model of PDAC," Teichmann was quoted as saying about the results.

In most animals, the tumor relapsed after three weeks of treatment, which modeled the situation in humans. "Often patients respond to a therapy and after a while, the tumor relapses," she added. "We can exploit this same tumor relapse in the mouse to investigate the resistance mechanism to improve the therapeutic strategy."

"The mutations trigger the onset of a signaling cascade that is necessary for the survival and proliferation of the cancer cells," Teichmann explained. "Our novel chemotherapeutic drug inhibits one essential protein of this cascade and therefore leads to the cascade's shutdown."

These findings encourage testing in mouse models rather than xenograft models. "Our results support testing novel agents for pancreatic cancer in endogenous mouse models, rather than conventional xenograft models because they take into account the genetic and morphological heterogeneity of the disease and may be more predictive with regard to efficacy," Teichmann concluded.

SOURCE: American Association for Cancer Research June 2012

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Health Care Services: Work Out Routines for Women: Why Visual ...

Expert Author NJ Rickman

The biggest problem with most work out plans for women is that they are designed by fitness trainers who focus mainly on building muscle. Now that's fine if you don't mind looking muscular; however, most women want to look lean and toned,but not like a smaller version of a male bodybuilder!

The common mantra of most trainers is that "Women don't have enough testosterone to build muscle." Really? Then how do you explain the bodies of female competitive cyclists or speed skaters? They tend to have huge thighs as a result of training hard. Many female swimmers have broad shoulders and muscular arms as a result of both weight training and the demands put on their upper body from their sport. Women CAN and DO build muscle!

Often, when a woman who wants to lose weight and tone up begins to work out at the gym with a trainer, she will notice that her jeans are starting to get a little bit tight at the thigh. She might mention this to her trainer, only to be dismissed and told to perform more squats and lunges.

You guessed it! Her thighs are getting increasingly large from this terrible advice. Frustrated because no one will listen to her concerns, the woman who was initially so excited by her progress ends up quitting exercising entirely. Consequently, she loses the muscle tone she sought out in the first place, and begins to pile her unwanted pounds back on. It's tragic, really.

Finally, someone has addressed women's fitness concerns and goals. Instead of trying to force women to become a junior version of The Hulk, Rusty Moore designed a spin-off of his highly popular "Visual Impact" work out plan just for women. Rusty himself is a long time bodybuilder who got fed up with the bulkiness he was developing. He realized that his ideal body was a lot more like Brad Pitt in "Fight Club" than it was with a huge, over-muscled body builder.

Taking the knowledge he gleaned from reducing his musculature from bodybuilder bulky to Brad Pitt sexy, Rusty decided that women were also in need of a program that would allow them to keep their feminine looks intact while losing unwanted fat and gaining a lean, yet curvy body in the process.

Rusty Moore's Visual Impact for Women is a revolutionary work out plan that flies in the face of conventional fitness programs. Rusty does not have you lifting heavy weights to failure, or performing squat after squat until your legs are shaking.

Rusty focuses more on cardio exercise in Visual Impact for Women to torch fat, while implementing low repetition work with weights. This is contrary to the what the majority of the fitness industry advises for women.

What's really special about Rusty's Visual Impact for Women is that Rusty has designed his program to fit your personal lifestyle. You will find work out plans for both gym and home, and also for four workouts a week and for three workouts per week. Highly flexible, and convenient for users.

Visual Impact's nutrition component is also different from much of what you see elsewhere. Instead of focusing on daily caloric intake, Rusty advices using weekly caloric intake instead. This change lets you have an odd glass of wine or nice dinner out without blowing your diet completely.

The two-pronged approach to fat burning and diet that visual impact provides can give you the body that you've been looking for.

Want to lose weight and get sexily toned without losing your feminine attributes? Go to http://visualimpactforwomenslim.blogspot.ca/ and watch Rusty's video about Visual Impact for Women today.

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Saturday, June 23, 2012

DELUSION SQUARED II music review by Salignac

5 stars The first album from Brittany based Delusion squared emerged in 2010 and impressed immediately on several fronts. It was a deeply involving concept album with a strong sci- fi/ecological theme, pitting the power of Mother nature against the evils of modern technology. The trio's music sounded mysterious and ethereal, recalling nothing less than a female fronted Porcupine tree. All those key ingredients are back for album N?2, which is a sequel to their debut. Divided into four distincts parts, II is endearingly meandering and highly complex. Lorraine Young's rich vocals are counterbalanced by Steve Francis's brutal guitar riffs and Emmanuel de Saint M?en's hypnotic keyboard pulses. A mesmerising record ! With a decent producer Delusion squared could become one of prog's all time greats.

Salignac | 5/5 |

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Augmented Reality Advertising: So Close, And Yet So Far Away

KAUST_ipad_02Nature Publishing Group teamed up with the King Abdullah University of Science and Technology to run an augmented reality advertising campaign. Point your tablet or smartphone at the print advertisement and watch the beautiful KAUST campus spring to life before you! You can click on the various departments, "talk" to virtual students, and peruse job openings hosted at Naturejobs.

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